Guidelines for Written Proposal

Page limits are double-spaced text.

Abstract (1 page): This section should concisely summarize the main points that will be developed within the body of the proposal (e.g., what is the purpose of the study, why is it important, what is the general strategy, etc.).
Specific Aims (2 pages): The proposal should have a small number (3-4) of well-chosen specific aims addressing a carefully constructed model. This section should clearly state the hypotheses to be tested and concisely describe the experiments that will be used to address these hypotheses.
Introduction (6 pages): This section should provide sufficient background information to allow the reader to understand the current knowledge in the field, the context for the proposed experiments, and their significance. References to pertinent literature should be included.
Research Plan and Methods (11 pages): This section must describe in detail the plan for pursuing each specific aim. In general the research plan will include the following topics:

Rationale for the experiments (specific data supporting the hypothesis, and how the proposed experiments will address/test the hypothesis).
Description of experimental procedures, with sufficient detail to indicate that the proposed experiments are feasible. Avoid unnecessary experimental detail (i.e. common procedures and reagents)
Expected outcomes, interpretation of results and discussion of possible pitfalls and alternative strategies. Use Text, avoiding figures of idalized experimental outcomes.
Overall conclusions that may be drawn from the experiments and future directions for research.

Literature Cited (no length limit): References should be provided for all statements not considered common knowledge. For each paper cited, include last names and initials of all authors (up to a total of 4-5), full title, journal, volume, and inclusive pagination. See Cell Press articles for examples.